Whenever you ask about an error message you need to state the full text
of the error message. "1606x53x295105304ox" means nothing.

Having a lot of programs installed does not slow your computer. (Having
a lot of programs /running/ can sometimes slow your computer.) However,
Windows Defragmenter needs at least 15% free space on the disk to run,
and one way to free up space is to uninstall programs you no longer use.

If you're having trouble uninstalling a program, you should ask the
program's technical support for help. If the program in question is a
Microsoft program, we can point you to an appropriate newsgroup.

The rule of thumb for failed uninstalls is to reinstall the program,
restart your computer and then uninstall the program. You usually need
to disable your security software (except for your firewall) when
installing and uninstalling software.

---
Leonard Grey
Errare humanum est

precious wrote:
> I keep getting one of two messages when I try to remove programs that I
> haven't used for along time, because my comoputer has slowed way down. I
> cant defrag or anything. One of the messages is: Error 1606 could not
> access network location % userprofile% /my pictures. Or I get
> 1606x53x295105304ox. Help!